Dolgacheva L P, Ginovker A G, Mironova G D
Parazitologiia. 1990 Nov-Dec;24(6):523-8.
By means of immunochemical methods a considerable increase in Ca(2+)-transporting glycoprotein (GP) in liver tissues of golden hamsters at early stages of opisthorchiasis has been established. On the 3rd day after the infection GP amount increases 6 fold, on the 7th day--15 fold. On the 14th day GP amount decreases but does not reach the control level. The control level is reached only on the 22nd day after the infection of animals. Ca(2+)-transporting GP belongs to the system of electrogenic transport of Ca2+ in mitochondria (MCh) and its increase in MCh of the liver is, apparently, the basis of destructive changes of these organelles.
通过免疫化学方法已确定，在 opisthorchiasis 早期，金黄仓鼠肝脏组织中钙转运糖蛋白（GP）显著增加。感染后第 3 天，GP 量增加 6 倍，第 7 天增加 15 倍。第 14 天 GP 量下降，但未达到对照水平。仅在动物感染后第 22 天达到对照水平。钙转运 GP 属于线粒体（MCh）中 Ca2+ 的电生成转运系统，其在肝脏 MCh 中的增加显然是这些细胞器破坏变化的基础。
