Department of Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Fertil Steril. 2010 Dec;94(7):2789-92. doi: 10.1016/j.fertnstert.2010.06.062. Epub 2010 Aug 2.
On the basis of the documented racial disparities in ectopic pregnancy incidence and mortality we hypothesized that African-American women with ectopic pregnancy would be more likely than white women to have treatment failure with methotrexate. In this retrospective cohort study, a racial disparity in methotrexate effectiveness was not found, but a significant relationship between low socioeconomic status and methotrexate failure was demonstrated.
基于已记录的宫外孕发病率和死亡率方面的种族差异,我们假设患有宫外孕的非裔美国女性使用甲氨蝶呤治疗失败的可能性比白人女性更高。在这项回顾性队列研究中,并未发现甲氨蝶呤疗效方面的种族差异,但确实表明低社会经济地位与甲氨蝶呤治疗失败之间存在显著关系。