Department of Pediatrics, Ton-Yen General Hospital, Hsinchu, Taiwan.
Pediatr Neonatol. 2010 Jun;51(3):178-81. doi: 10.1016/S1875-9572(10)60033-2.
The purpose of this study was to compare resting energy expenditure (REE) in premature infants of different body weights during weaning from the incubator. We hypothesized that premature infants would respond to weaning from an incubator with an increase in REE, and that the increment would be larger in infants with lower body weights than in those with higher body weights.
Stable preterm infants with body weights between 1800-2200 g were enrolled. REE was measured using indirect calorimetry at 1 hour before weaning and 3 hours after turning off the incubator. REE measurements from infants with higher body weight (2000-2200 g, Group A) were compared to those of infants with lower body weight (1800-2000 g, Group B).
A total of 22 patients were studied (10 in Group A and 12 in Group B). REE increased significantly after weaning in both groups (Group A: from 62 +/- 7 kcal/kg/day to 69 +/- 8 kcal/kg/day, p = 0.045 and Group B: from 65 +/- 5 kcal/kg/day to 70 +/- 7 kcal/kg/day, p = 0.001). However, there was no significant difference in REE increments between the two groups.
REE increased significantly in infants during weaning from an incubator. The increase in REE increment was similar in smaller (1800-2000 g) and larger (2000-2200 g) babies in this study. Weaning of preterm babies from an incubator may be safely started when their body weight reaches 1800 g.
本研究旨在比较不同体重早产儿从保温箱中离温时的静息能量消耗（REE）。我们假设早产儿在从保温箱中离温时会增加 REE，并且体重较低的婴儿比体重较高的婴儿的增量会更大。
纳入体重在 1800-2200 克之间的稳定早产儿。在离温前 1 小时和关闭保温箱后 3 小时使用间接热量法测量 REE。将体重较高（2000-2200 克，A 组）的婴儿的 REE 测量值与体重较低（1800-2000 克，B 组）的婴儿进行比较。
共有 22 名患者入组（A 组 10 例，B 组 12 例）。两组 REE 在离温后均显著增加（A 组：从 62±7 千卡/公斤/天增加至 69±8 千卡/公斤/天，p=0.045；B 组：从 65±5 千卡/公斤/天增加至 70±7 千卡/公斤/天，p=0.001）。但是，两组间 REE 增量无显著差异。
早产儿从保温箱中离温时 REE 显著增加。在本研究中，较小（1800-2000 克）和较大（2000-2200 克）婴儿的 REE 增量增加相似。当早产儿体重达到 1800 克时，可以安全地开始从保温箱中离温。
