Ovental Amit, Lubetzky Ronit, Marom Ronella, Berger Irit, Raskind Craig, Haham Alon, Mandel Dror
Department of Neonatology, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Department of Pediatrics, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
Harefuah. 2020 Oct;159(10):721-725.
We have recently showed that Wolfgang Amadeus Mozart's music significantly lowers resting energy expenditure (REE) in preterm infants. Whether or not this effect is specific to Mozart is unknown.
To study whether familiar ("ethnic") music has the same effect on REE in preterm infants as music by Mozart.
A prospective, randomized clinical trial with cross-over was conducted in 9 healthy, appropriate weights for gestational age, gavage fed, preterm infants. Infants were randomized to be exposed to a 30-minute period of Mozart music or "ethnic" music or no music over 3 consecutive days. Metabolic measurements were performed by indirect calorimetry.
A total of 27 REE measurements were performed. On average REE was lower in preterm infants who were exposed to "ethnic" music compared to preterm infants who were exposed to music by Mozart (p=0.388). REE was lower in preterm infants who didn't listen to music at all compared to Mozart (p=0.014) or to "ethnic" (p=0.134).
Exposure to music by Mozart significantly elevated REE in healthy preterm infants compared to preterm infants who didn't listen to music at all. Nevertheless a trend of lower REE was demonstrated when preterm infants listened to "ethnic" music compared to Mozart.
We were unable to demonstrate a significant decrease in REE by exposure of preterm infants to Mozart- or "familiar" music. At this time point we cannot recommend music therapy for preterm infants in order to lower the REE. We speculate that a larger study sample might show a definite effect.
我们最近发现，沃尔夫冈·阿玛多伊斯·莫扎特的音乐能显著降低早产儿的静息能量消耗（REE）。这种效果是否特定于莫扎特的音乐尚不清楚。
研究熟悉的（“民族”）音乐对早产儿REE的影响是否与莫扎特的音乐相同。
对9名健康、体重适合孕周、经口喂养的早产儿进行了一项前瞻性、随机交叉临床试验。婴儿被随机分为三组，连续三天每天接受30分钟的莫扎特音乐、“民族”音乐或无音乐刺激。通过间接测热法进行代谢测量。
共进行了27次REE测量。平均而言，与接触莫扎特音乐的早产儿相比，接触“民族”音乐的早产儿REE较低（p = 0.388）。与接触莫扎特音乐（p = 0.014）或“民族”音乐（p = 0.134）的早产儿相比，完全不聆听音乐的早产儿REE较低。
与完全不聆听音乐的早产儿相比，接触莫扎特音乐能显著提高健康早产儿的REE。然而，与莫扎特音乐相比，早产儿聆听“民族”音乐时REE有降低趋势。
我们未能证明让早产儿接触莫扎特音乐或“熟悉”音乐能使REE显著降低。在这个时间点，我们不建议为降低REE而对早产儿进行音乐治疗。我们推测更大的研究样本可能会显示出明确的效果。
