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印度昌迪加尔流浪狗和家养狗中狂犬病抗体的流行情况。

Prevalence of rabies antibodies in street and household dogs in Chandigarh, India.

作者信息

Singh Mini P, Goyal Kapil, Majumdar Manasi, Ratho Radha Kanta

机构信息

Department of Virology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

出版信息

Trop Anim Health Prod. 2011 Jan;43(1):111-4. doi: 10.1007/s11250-010-9661-8. Epub 2010 Jul 31.

Abstract

The present study reports the first survey for the detection of antirabies antibodies in street and household dogs in India. We aimed to check the efficacy of control programs for the disease in the Union territory of Chandigarh. The serum samples were collected from 100 street and 50 household dogs and tested for the presence of antirabies antibodies by ELISA. As per WHO criteria, a titre of >0.5 IU/ml of antirabies antibody in serum samples was taken as the protective level. Protective antirabies antibody titre was found only in 1% of the street dogs and 16% of the pet dogs. The awareness among the pet dog owners about the antirabies vaccination schedule was low as 18% did not know the vaccination status of the dog and 66% had got the initial immunization done with only three doses and annual boosters were not given. A National Rabies Elimination Program needs to be launched as a collaborative venture by both medical and veterinary practitioners to curb this deadly disease. Also periodic surveys to test the status of antirabies IgG among dogs need to be carried out to ascertain the attainment of WHO protective levels.

摘要

本研究报告了印度首次针对街头犬和家养犬抗狂犬病抗体检测的调查。我们旨在检验印度昌迪加尔联合属地该疾病防控项目的成效。从100只街头犬和50只家养犬采集血清样本,并用酶联免疫吸附测定法检测抗狂犬病抗体的存在情况。根据世界卫生组织标准,血清样本中抗狂犬病抗体滴度>0.5国际单位/毫升被视为保护水平。仅在1%的街头犬和16%的宠物犬中发现了保护性抗狂犬病抗体滴度。宠物犬主人对狂犬病疫苗接种计划的知晓度较低,18%的人不知道犬的疫苗接种情况,66%的人仅完成了三剂初始免疫,未进行年度加强免疫。需要由医学和兽医从业者联合开展一项全国性的狂犬病消除计划,以遏制这种致命疾病。此外,需要定期进行调查,检测犬类中抗狂犬病IgG的状况,以确定是否达到世界卫生组织的保护水平。

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