Department of Preventive Medicine, Kaunas University of Medicine, Eiveniu 4, 50161 Kaunas, Lithuania.
Medicina (Kaunas). 2010;46(5):351-9.
Breast cancer is the most common cancer among women, comprising about 23% of all cancer types. About 1300 new cases of breast cancer are registered in Lithuania annually. During the last decade, health-related quality of life has become an important part of breast cancer treatment. Pain, fatigue, and sleep disorders are important aspects of health-related quality of life. The aim of the study was to evaluate health-related quality of life (HRQL) among patients with breast cancer in Lithuania. The main tasks were to analyze HRQL in sociodemographic and clinical aspects, and to determine symptoms that have the greatest impact on HRQL .
A cross-sectional study was carried out in four major Lithuanian hospitals. An EORTC QLQ-C30 (version 3) questionnaire with general demographic and medical information was distributed among 318 patients. A total of 284 patients were included in the analysis.
The response rate was 89%. The mean age of patients was 55.9 years (SD, 10.1 years), and the mean time from diagnosis--2.36 years (SD, 3.2 years). A greater part (65%) of the studied women lived in a family or with a partner. Women reported high level of functioning across several standardized HRQOL scales: cognitive functioning, everyday activity, and physical functioning. Fatigue and sleeping disorders were the most commonly indicated symptoms in the symptom scale. Fatigue and pain were the most important factors affecting general HRQOL.
Our results emphasize that the general HRQOL of the studied women is fair, but poorer than that of the corresponding population in other countries. Women living in a family or partnership experienced fewer financial troubles and had higher HRQOL scores across several standardized measures compared to those who were single. Women with late stages of breast cancer felt worse and were less socially active compared to women who were diagnosed with early-stage breast cancer.
乳腺癌是女性最常见的癌症,约占所有癌症类型的 23%。立陶宛每年约有 1300 例新的乳腺癌病例。在过去的十年中,健康相关生活质量已成为乳腺癌治疗的重要组成部分。疼痛、疲劳和睡眠障碍是健康相关生活质量的重要方面。本研究的目的是评估立陶宛乳腺癌患者的健康相关生活质量(HRQL)。主要任务是分析社会人口学和临床方面的 HRQL,并确定对 HRQL 影响最大的症状。
在立陶宛的四家主要医院进行了一项横断面研究。向 318 名患者发放了 EORTC QLQ-C30(第 3 版)问卷,其中包含一般人口统计学和医学信息。共有 284 名患者纳入分析。
应答率为 89%。患者的平均年龄为 55.9 岁(标准差为 10.1 岁),诊断后平均时间为 2.36 年(标准差为 3.2 年)。研究中的大部分女性(65%)居住在家庭或与伴侣一起生活。女性在几个标准化 HRQOL 量表中报告了高水平的功能:认知功能、日常活动和身体功能。疲劳和睡眠障碍是症状量表中最常见的症状。疲劳和疼痛是影响总体 HRQOL 的最重要因素。
我们的研究结果强调,研究中女性的总体 HRQOL 尚可,但不如其他国家相应人群的 HRQOL。与单身女性相比,居住在家庭或伴侣关系中的女性在财务方面遇到的困难较少,在几个标准化指标上的 HRQOL 评分也更高。与早期乳腺癌诊断的女性相比,晚期乳腺癌女性的感觉更差,社交活动也较少。