Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonggi-do, Korea.
J Neurogastroenterol Motil. 2010 Jul;16(3):291-8. doi: 10.5056/jnm.2010.16.3.291. Epub 2010 Jul 27.
BACKGROUND/AIMS: Gastroesophageal reflux disease is one of the most common and frequent chronic disease requiring considerable cost. We investigated the medical care costs in the erosive reflux disease (ERD) and non-erosive reflux disease (NERD).
The risk factors and the direct medical care costs were analyzed retrospectively in the ERD (178 patients) and NERD (183 patients) groups for a follow up period of 2 years.
Logistic regression analysis showed that the ERD was more frequent in the groups of male gender, alcohol consumption, higher body mass index (>/=25 kg/m(2)), hiatal hernia, and higher triglyceride levels (>/=150 mg/dL). The direct medical care costs per person for 2 years were found to be $384.8 (ERD) and $412.9 (NERD) without statistically significant differences (p = 0.364). However, 9.3% (17/183) of the NERD patients had visited the emergency room compared to 3.4% (6/178) of the ERD patients (p = 0.029). In addition, more NERD patients were hospitalized than ERD patients (p = 0.006), and because of the longer hospitalization period, the medical costs in NERD patients were higher than ERD patients (p = 0.038).
In spite of the different risk factors for ERD and NERD, total direct medical care costs were similar between the ERD and NERD group. However, more visits to emergency room and longer hospitalization period with more hospitalization costs in NERD patients account for the differences in medical service and usage distribution between the 2 groups.
背景/目的:胃食管反流病是最常见和最频繁的慢性疾病之一,需要大量的医疗费用。我们研究了糜烂性反流病(ERD)和非糜烂性反流病(NERD)的医疗费用。
对 ERD(178 例)和 NERD(183 例)组进行了为期 2 年的随访,回顾性分析了危险因素和直接医疗费用。
Logistic 回归分析显示,男性、饮酒、体重指数(>/=25 kg/m(2))、食管裂孔疝和甘油三酯水平(>/=150 mg/dL)较高的患者更易发生 ERD。2 年内每人的直接医疗费用分别为 384.8 美元(ERD)和 412.9 美元(NERD),差异无统计学意义(p = 0.364)。然而,183 例 NERD 患者中有 9.3%(17/183)曾就诊于急诊室,而 ERD 患者中仅有 3.4%(6/178)(p = 0.029)。此外,NERD 患者的住院人数多于 ERD 患者(p = 0.006),并且由于住院时间较长,NERD 患者的医疗费用高于 ERD 患者(p = 0.038)。
尽管 ERD 和 NERD 的危险因素不同,但 ERD 和 NERD 组的直接总医疗费用相似。然而,NERD 患者更多地就诊于急诊室,住院时间更长,住院费用更高,这导致了两组之间医疗服务和使用分布的差异。