三氯化铌催化的炔烃和α,ω-二烯的分子间[2+2+2]环加成反应：高化学选择性和区域选择性合成 5-ω-烯基-1,4-取代-1,3-环己二烯衍生物。
NbCl3-catalyzed intermolecular [2+2+2] cycloaddition of alkynes and alpha,omega-dienes: highly chemo- and regioselective formation of 5-omega-alkenyl-1,4-substituted-1,3-cyclohexadiene derivatives.
机构信息
Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering and ORDIST, Kansai University, Suita, Osaka 564-8680, Japan.
出版信息
J Org Chem. 2010 Sep 3;75(17):6046-9. doi: 10.1021/jo101229u.
PMID:20681534
Abstract
Intermolecular [2+2+2] cycloaddition of tert-butylacetylene with alpha,omega-dienes was successfully achieved by NbCl(3)(DME) catalyst to afford 5-omega-alkenyl-1,4-disubstituted-1,3-cyclohexadienes in excellent yields with high chemo- and regioselectivity.
摘要
三氯化铌（DME）催化剂促进叔丁基乙炔与α,ω-二烯的分子间[2+2+2]环加成反应，以高产率和高化学选择性及区域选择性得到 5-ω-烯基-1,4-二取代-1,3-环己二烯。
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