Protasis/MRM Corporation, 101 West Tomaras Avenue, Savoy, Illinois 61874, USA.
Anal Chem. 2010 Sep 1;82(17):7227-36. doi: 10.1021/ac101003f.
A new generation of microscale, nuclear magnetic resonance (CapNMR) probe technology employs two independent detection elements to accommodate two samples simultaneously. Each detection element in the dual-sample CapNMR probe (DSP) delivers the same spectral resolution and S/N as in a CapNMR probe configured to accommodate one sample at a time. A high degree of electrical isolation allows the DSP to be used in a variety of data acquisition modes. Both samples are shimmed simultaneously to achieve high spectral resolution for simultaneous data acquisition, or alternatively, a flowcell-specific shim set is readily called via spectrometer subroutines to enable acquisition from one sample while the other is being loaded. An automation system accommodates loading of two samples via dual injection ports on an autosampler and two completely independent flowpaths leading to dedicated flowcells in the DSP probe.
新一代微尺度、核磁共振(CapNMR)探头技术采用两个独立的检测元件,可同时容纳两个样品。双样品 CapNMR 探头(DSP)中的每个检测元件都能提供与每次仅容纳一个样品的 CapNMR 探头相同的光谱分辨率和 S/N。高度的电隔离允许 DSP 以各种数据采集模式使用。两个样品同时进行匀场,以实现高光谱分辨率的同时数据采集,或者,通过光谱仪子程序调用特定于流池的匀场设置,以便在加载另一个样品的同时从一个样品进行采集。自动化系统通过自动进样器上的两个双注射口和两个完全独立的通向 DSP 探头专用流池的流路来容纳两个样品的加载。