Fisher G, Petucci C, MacNamara E, Raftery D
Department of Chemistry, Purdue University, West Lafayette, Indiana 47907-1393, USA.
J Magn Reson. 1999 May;138(1):160-3. doi: 10.1006/jmre.1999.1725.
A dual channel probe for the simultaneous acquisition of NMR data from multiple samples has been developed. This multiplex probe consists of two noninteracting sample coils that are each capable of detecting NMR signals at the same resonant frequency with good sensitivity and resolution. 13C free induction decays for the two samples, methanol (13C, 99%) and carbon tetrachloride (13C, 99%), were acquired simultaneously at 75.44 MHz using a single transmitter pulse and separate NMR receivers. S/N measurements are comparable to those observed using single coils. No evidence of cross talk is evident in the spectra even after considerable signal averaging. The probe demonstrates the feasibility of significant parallelism in NMR, which will be of interest in situations where high throughput analysis is desired.
已开发出一种用于同时从多个样品采集核磁共振(NMR)数据的双通道探头。这种多路复用探头由两个互不干扰的样品线圈组成,每个线圈都能够在相同的共振频率下以良好的灵敏度和分辨率检测NMR信号。使用单个发射脉冲和独立的NMR接收器,在75.44 MHz下同时采集了两个样品甲醇(13C,99%)和四氯化碳(13C,99%)的13C自由感应衰减信号。信噪比测量结果与使用单个线圈时观察到的结果相当。即使经过大量信号平均,光谱中也没有明显的串扰迹象。该探头证明了NMR中显著并行性的可行性,这在需要高通量分析的情况下将具有重要意义。