青少年物质使用障碍的神经生物学：预防和治疗的意义。
Neurobiology of adolescent substance use disorders: implications for prevention and treatment.
机构信息
Yale Child Study Center, Yale University School of Medicine, 230 South Frontage Road, New Haven, CT 06520, USA.
出版信息
Child Adolesc Psychiatr Clin N Am. 2010 Jul;19(3):479-92. doi: 10.1016/j.chc.2010.03.003.
Abstract
Adolescence represents a unique period of development with neuronal maturation accompanied by increases in behavioral risk taking. Although risky behavior is a likely marker of normative adolescent development, there is an early emergence of substance use disorders in this population. Adolescence represents a distinct period of vulnerability to substance use initiation and transitions to substance abuse and dependence. Of recent interest is understanding the neurobiology of adolescent substance use disorders, with adult studies being limited in their applicability to this developmentally sensitive maturation period and providing restricted insight into potential treatment and intervention. First, the authors review the neurobiology of adolescent substance use disorders and, second, the authors consider the implications of these findings for prevention and treatment.
摘要
青春期是一个独特的发展阶段，伴随着神经元成熟，行为冒险行为增加。尽管冒险行为可能是青少年正常发展的标志，但在这个群体中，物质使用障碍很早就出现了。青春期是易发生物质使用开始、向滥用和依赖过渡的独特时期。最近人们对青少年物质使用障碍的神经生物学感兴趣，而成人研究在其适用性方面受到限制，对潜在的治疗和干预措施的了解也很有限。首先，作者回顾了青少年物质使用障碍的神经生物学，其次，作者考虑了这些发现对预防和治疗的影响。
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