初步鉴定仓鼠模型中源自 Mus musculus 的致病性 Leptospira borgpetersenii 血清群 Ballum 菌株。
Preliminary characterization of Mus musculus-derived pathogenic strains of Leptospira borgpetersenii serogroup Ballum in a hamster model.
机构信息
Centro de Biotecnologia and Departamento de Microbiologia e Parasitologia, Universidade Federal de Pelotas Pelotas, Rio Grande do Sul, Brazil.
出版信息
Am J Trop Med Hyg. 2010 Aug;83(2):336-7. doi: 10.4269/ajtmh.2010.10-0120.
Abstract
Human and animal leptospirosis caused by Leptospira spp. belonging to serogroup Ballum has increased worldwide in the past decade. We report the isolation and serologic and molecular characterization of four L. borgpetersenii serogroup Ballum isolates obtained from Mus musculus, and preliminary virulence studies. These isolates are useful for diagnosis of leptospirosis and for epidemiologic studies of its virulence and pathogenic mechanisms.
摘要
在过去十年中，由归属于血清群波尔顿氏菌的螺旋体属引起的人类和动物钩端螺旋体病在世界范围内有所增加。我们报告了从小家鼠中分离出的 4 株波尔顿氏菌血清群波尔顿氏菌的分离株的血清学和分子特征，并进行了初步的毒力研究。这些分离株可用于钩端螺旋体病的诊断，以及对其毒力和发病机制的流行病学研究。
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