Furukawa Maiko, Kasajima Saeko, Nakamura Yuri, Shouzushima Meiko, Nagatani Naho, Takinishi Akira, Taguchi Ayumi, Fujita Mikiko, Niimi Akiko, Misaka Ryoichi, Nagahara Hikaru
Aoyama Hospital, Tokyo Women's Medical University.
Intern Med. 2010;49(15):1537-40. doi: 10.2169/internalmedicine.49.3509. Epub 2010 Aug 2.
Herbal preparations are widely available and often regarded by the public as harmless remedies for a variety of medical ailments. However, some of these products or their metabolites can cause adverse effects such as liver damage. In this case report a 53-year-old female taking shou-wu-pian for 8 months presented with acute hepatitis. Histopathological assessment of liver tissue obtained by biopsy was consistent with a toxic reaction. Clinical and biochemical resolution was brought about following cessation of the drug. It is important for clinicians to consider Chinese herbal preparations as a potential cause of abnormal liver function test results.
草药制剂随处可得，公众通常认为它们是治疗各种疾病的无害药物。然而，其中一些产品或其代谢物可能会引起不良反应，如肝损伤。在本病例报告中，一名53岁女性服用首乌片8个月后出现急性肝炎。通过活检获得的肝组织病理评估结果与毒性反应一致。停药后临床和生化指标恢复正常。临床医生应将中草药制剂视为肝功能检查结果异常的潜在原因，这一点很重要。
