Murashov Alexander K
Department of Physiology, East Carolina University, School of Medicine, Greenville, NC, USA.
Methods Mol Biol. 2010;650:15-25. doi: 10.1007/978-1-60761-769-3_2.
Recently, RNAi, including microRNAs (miRNAs), has become an important tool to investigate the regulatory mechanism of stem cell maintenance and differentiation. In this short chapter, we will give a brief overview of the discovery history, functions, and mechanisms of RNAi and miRNAs. We will also discuss RNAi as a tool to study stem cell function and the potential future practical applications.
最近，包括微小RNA（miRNA）在内的RNA干扰已成为研究干细胞维持和分化调控机制的重要工具。在这一简短章节中，我们将简要概述RNA干扰和微小RNA的发现历史、功能及机制。我们还将讨论RNA干扰作为研究干细胞功能的工具以及未来潜在的实际应用。
