Murashov Alexander K
Department of Physiology, East Carolina University School of Medicine, 6N-98, 600 Moye Blvd, Greenville, NC, 27834, USA.
Methods Mol Biol. 2017;1622:15-25. doi: 10.1007/978-1-4939-7108-4_2.
Recently, RNAi and microRNAs (miRNAs) have become important tools to investigate the regulatory mechanism of stem cell maintenance and differentiation. In this short review, we give a brief overview of the discovery history, functions, and mechanisms of RNAi and miRNAs. We also discuss the RNAi as a tool to study the stem cell function and the potential future practical applications.
最近，RNA干扰（RNAi）和微小RNA（miRNA）已成为研究干细胞维持和分化调控机制的重要工具。在这篇简短的综述中，我们简要概述了RNAi和miRNA的发现历史、功能及机制。我们还讨论了RNAi作为研究干细胞功能的工具以及未来潜在的实际应用。
