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Catalytic asymmetric conjugate addition and allylic alkylation with Grignard reagents.格氏试剂催化的不对称共轭加成和烯丙基烷基化反应。
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Enantioselective copper-catalyzed conjugate addition and allylic substitution reactions.对映选择性铜催化共轭加成和烯丙基取代反应。
Chem Rev. 2008 Aug;108(8):2796-823. doi: 10.1021/cr0683515. Epub 2008 Aug 1.
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Asymmetric Ni-catalyzed conjugate allylation of activated enones.不对称镍催化的活性烯酮共轭烯丙基化反应。
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Catalytic conjugate addition of allyl groups to styryl-activated enones.烯丙基对苯乙烯基活化烯酮的催化共轭加成反应。
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Palladium- and copper-catalyzed 1,4-additions of organozinc compounds to conjugated aldehydes.
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Rhodium-catalyzed carbonylative arylation of alkynes with arylboronic acids: an efficient and straightforward method in the synthesis of 5-aryl-2(5H)-furanones.
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Metallophosphite-induced nucleophilic acylation of alpha,beta-unsaturated amides: facilitated catalysis by a diastereoselective retro [1,4] Brook rearrangement.亚磷酸金属盐引发的α,β-不饱和酰胺的亲核酰化反应：通过非对映选择性逆向[1,4]布鲁克重排实现的催化促进作用
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New synthesis of 1,4-diketones via rhodium-catalysed 1,4 carbonylative addition of arylboronic acids to alpha,beta-unsaturated ketones.
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钯催化的二烷基锌试剂与不饱和羰基化合物的羰基共轭加成反应。

Pd-catalyzed carbonylative conjugate addition of dialkylzinc reagents to unsaturated carbonyls.

机构信息

Department of Chemistry, Merkert Chemistry Center, Boston College, Chestnut Hill, Massachusetts 02467, USA.

出版信息

Org Lett. 2010 Sep 3;12(17):3760-3. doi: 10.1021/ol1013476.

DOI:10.1021/ol1013476
PMID:20687574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2929296/
Abstract

The Pd-catalyzed addition of organozinc reagents to unsaturated carbonyls in the presence of carbon monoxide provides 1,4-diketones in good yield. The reaction was studied with a number of substituted cyclic and acyclic ketones as well as alpha,beta-unsaturated aldehydes.

摘要

在一氧化碳存在下，钯催化的有机锌试剂对不饱和羰基的加成反应提供了 1,4-二酮，产率良好。该反应研究了许多取代的环状和非环状酮以及α，β-不饱和醛。