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基于阴离子四电子供体的钯环配合物作为芳基硼酸与α,β-不饱和酮、醛和α-酮酯加成反应的催化剂。

Anionic four-electron donor-based palladacycles as catalysts for addition reactions of arylboronic acids with alpha,beta-unsaturated ketones, aldehydes, and alpha-ketoesters.

作者信息

He Ping, Lu Yong, Dong Cheng-Guo, Hu Qiao-Sheng

机构信息

Department of Chemistry, College of Staten Island and the Graduate Center of the City University of New York, Staten Island, New York 10314, USA.

出版信息

Org Lett. 2007 Jan 18;9(2):343-6. doi: 10.1021/ol062814b.

DOI:10.1021/ol062814b
PMID:17217300
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2597418/
Abstract

Anionic four-electron donor-based palladacycle-catalyzed 1,4-additions of arylboronic acids with alpha,beta-unsaturated ketones and 1,2-additions of arylboronic acids with aldehydes and alpha-ketoesters are described. Our study demonstrated that palladacycles were highly efficient, practical catalysts for these addition reactions. The work described here not only opened a new paradigm for the application of palladacycles, but may also pave the road for other metalacycles as practically useful catalysts for such addition reactions including asymmetric ones. [reaction: see text].

摘要

本文描述了基于阴离子四电子供体的钯环催化芳基硼酸与α,β-不饱和酮的1,4-加成反应，以及芳基硼酸与醛和α-酮酸酯的1,2-加成反应。我们的研究表明，钯环是这些加成反应的高效实用催化剂。本文所述工作不仅为钯环的应用开辟了新的范例，也可能为其他金属环作为此类加成反应（包括不对称反应）的实用催化剂铺平道路。[反应：见正文]

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Rhodium-Catalyzed Addition of Organoboronic Acids to Aldehydes.铑催化有机硼酸与醛的加成反应
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Rhodium-catalyzed addition of arylboronic acids to isatins: an entry to diversity in 3-aryl-3-hydroxyoxindoles.铑催化芳基硼酸与异吲哚酮的加成反应：通往3-芳基-3-羟基氧化吲哚多样性的途径
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Rhodium-catalyzed asymmetric addition of aryl- and alkenylboronic acids to isatins.铑催化芳基硼酸和烯基硼酸对异吲哚酮的不对称加成反应。
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