Tumour Biology and Angiogenesis Department, Genentech Inc, 1 DNA Way, South San Francisco, CA 94080, USA.
BMC Biol. 2010 Jul 29;8:102. doi: 10.1186/1741-7007-8-102.
The Hedgehog (Hh) signaling pathway differentially utilizes the primary cilium in mammals and fruit flies. Recent work, including a study in BMC Biology, demonstrates that Hh signals through the cilium in zebrafish, clarifying the evolution of Hh signal transduction. See research article: http://www.biomedcentral.com/1741-7007/8/65.
刺猬（Hh）信号通路在哺乳动物和果蝇中差异地利用初级纤毛。最近的研究工作，包括在 BMC 生物学中的一项研究，表明 Hh 在斑马鱼中通过纤毛传递信号，阐明了 Hh 信号转导的进化。参见研究文章：http://www.biomedcentral.com/1741-7007/8/65。
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