School of Resource and Environmental Engineering, East China University of Science and Technology, Shanghai 200237, China.
Exp Parasitol. 2011 Jan;127(1):238-42. doi: 10.1016/j.exppara.2010.08.002. Epub 2010 Aug 6.
DNA sequence analysis of the 60 kDa glycoprotein (gp60) gene has been used extensively in subtyping Cryptosporidium hominis in humans and Cryptosporidium parvum in humans and ruminants. In this study, nucleotide sequences of the gp60 gene were obtained from seven Cryptosporidium species and genotypes related to the two species. Altogether, seven subtype families were detected, including four new subtype families. These data should be useful in studies of the transmission and zoonotic potential of cryptosporidiosis in mice and small wild mammals.
对 60 kDa 糖蛋白(gp60)基因的 DNA 序列分析已广泛用于对人和反刍动物中感染的人源隐孢子虫和小隐孢子虫进行亚型分型。在本研究中,从七种与这两种生物相关的隐孢子物种和基因型中获得了 gp60 基因的核苷酸序列。总共检测到七个亚型家族,包括四个新的亚型家族。这些数据应该有助于研究隐孢子虫病在小鼠和小型野生哺乳动物中的传播和动物源性。