Department of Endocrinology, Diabetes and Rheumatology, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany.
Lupus. 2010 Aug;19(9):1087-95. doi: 10.1177/0961203310374304.
Skin discolorations and skin lesions due to vascular pathologies are common clinical features in systemic lupus erythematosus. A variety of clinical manifestations such as Raynaud's phenomenon, acrocyanosis, livedo patterns, erythematous or violaceous macules and papules or necrosis are triggered by heterogeneous pathophysiological mechanisms such as vasospasm, vasculitis or thromboembolism. A standardized macro- and microvascular assessment is necessary to establish the correct diagnosis. We describe and illustrate common clinical features of vascular skin manifestations in systemic lupus erythematosus and present a diagnostic algorithm.
由于血管病变导致的皮肤变色和皮肤损伤是系统性红斑狼疮的常见临床特征。各种临床表现，如雷诺现象、肢端发绀、网状青斑、红斑或紫红色斑丘疹或坏死，是由血管痉挛、血管炎或血栓栓塞等不同的病理生理机制引起的。为了确立正确的诊断，需要进行标准化的宏观和微观血管评估。我们描述并说明了系统性红斑狼疮血管皮肤表现的常见临床特征，并提出了一个诊断算法。
