Arrese Estrada J, Mélotte P, Hermanns J F, Piérard G E
Service de Dermatopathologie, Université de Liège, Belgique.
Ann Dermatol Venereol. 1991;118(4):277-9.
We have looked for the presence of Borrelias by immunohistochemistry in cutaneous biopsies taken from patients with positive Borrelia serology. We used the monoclonal antibody "P41 Borrelia burgdorferi flagellin". We found Borrelias in the dermis of Pick-Herxheimer disease (3/3), erythema chronicum migrans (6/9), lymphocytoma (1/3), and morpheas (2/5). They were also seen in the vascular wall of hypodermal arterioles in a case of cutaneous periarteritis nodosa (1/2). Treponema pallidum was not revealed by the antibody.
我们通过免疫组织化学方法,在血清学检测伯氏疏螺旋体呈阳性的患者的皮肤活检样本中寻找伯氏疏螺旋体的存在。我们使用了单克隆抗体“伯氏疏螺旋体鞭毛蛋白P41”。我们在变应性亚败血症(3/3)、慢性游走性红斑(6/9)、淋巴细胞瘤(1/3)和硬斑病(2/5)患者的真皮层中发现了伯氏疏螺旋体。在1例皮肤结节性动脉周围炎患者的皮下小动脉血管壁中也发现了伯氏疏螺旋体(1/2)。该抗体未检测到梅毒螺旋体。