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孤立性皮肤良性淋巴腺病的螺旋体病因。

The spirochetal etiology of lymphadenosis benigna cutis solitaria.

作者信息

Hovmark A, Asbrink E, Olsson I

出版信息

Acta Derm Venereol. 1986;66(6):479-84.

PMID:2433866
Abstract

Ten patients with a clinical diagnosis of lymphadenosis benigna cutis (LABC) solitaria were investigated. Four of the patients knew that they had received a tick bite during the year prior to the appearance of the LABC lesion. Five patients had had a migrating erythema, indicating a previous erythema chronicum migrans Afzelius, near the site where the LABC lesion had developed. In one patient meningitis and a facial palsy occurred. Elevated titers of antibodies against Borrelia spirochetes were found in sera from six of nine patients. Spirochetes were cultivated from one out of two biopsies from LABC lesions. The clinical findings, the results of the serologic tests and the successful cultivation of spirochetes show that Ixodes ricinus-transmitted Borrelia spirochetes can cause LABC solitaria.

摘要

对10例临床诊断为孤立性皮肤良性淋巴腺病(LABC)的患者进行了调查。其中4例患者知道在LABC病变出现前一年曾被蜱叮咬。5例患者曾出现游走性红斑,表明在LABC病变发生部位附近曾有过慢性游走性红斑(Afzelius型)。1例患者发生了脑膜炎和面瘫。9例患者中有6例血清中抗疏螺旋体抗体滴度升高。从LABC病变的两份活检标本中有一份培养出了螺旋体。临床发现、血清学检测结果以及螺旋体的成功培养表明,蓖麻硬蜱传播的疏螺旋体可引起孤立性LABC。

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The spirochetal etiology of lymphadenosis benigna cutis solitaria.孤立性皮肤良性淋巴腺病的螺旋体病因。
Acta Derm Venereol. 1986;66(6):479-84.
2
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Infection. 1996 Jan-Feb;24(1):80-4. doi: 10.1007/BF01780665.
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Antigenic stability of Borrelia burgdorferi during chronic infections of immunocompetent mice.伯氏疏螺旋体在免疫健全小鼠慢性感染期间的抗原稳定性
Infect Immun. 1993 Dec;61(12):4955-61. doi: 10.1128/iai.61.12.4955-4961.1993.
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J Clin Microbiol. 1988 Feb;26(2):338-46. doi: 10.1128/jcm.26.2.338-346.1988.
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