School of Biomedical Sciences, University of Ulster, Coleraine, UK.
Graefes Arch Clin Exp Ophthalmol. 2011 Apr;249(4):607-12. doi: 10.1007/s00417-010-1476-9. Epub 2010 Aug 6.
Advances in the optical design of soft contact lenses have seen certain manufacturers incorporate aspheric optics into soft lenses in an attempt to reduce spherical aberration, to provide superior visual performance. The aim of this study is to determine the on-eye differences in spherical aberration and higher order aberrations (HOA) between the Bausch and Lomb PureVision (Balafilcon A) and the CooperVision Biofinity (Comfilcon A).
Twenty subjects were recruited in a prospective, randomized, unilateral study. The right eye was dilated and HOA measured with the NIDEK OPD-Scan. Each eye was fitted randomly with a -3.00D PureVision and a -3.00D Biofinity, and HOA were measured with lenses in situ across a 6 mm pupil. Paired t-tests were performed to determine HOA differences with the lenses in situ compared to baseline.
Aberrometry was successfully performed on all subjects. Statistical analysis indicated no changes in spherical aberration, but changes in other HOA. With the PureVision, there were increases in Zernike terms Z (3) (1) (from 0.01 μm to -0.11 μm), Z (4) (-2) (from 0.01 μm to 0.13 μm) and Z (5) (-1) (from -0.01 μm to 0.03 μm). With the Biofinity there was an increase in Zernike term Z (3) (3) (from 0.00 μm to 0.09 μm).
No statistically significant changes occurred in spherical aberration. The PureVision caused statistically significant increases in Z (3) (1) , Z (4) (-2) and Z (5) (-1) , and the Biofinity caused an increase in Z (3) (3) . Clinically significant changes (>0.1 μm) occurred with terms Z (3) (1) and Z (4) (-2) with the PureVision only.
软性隐形眼镜光学设计的进步使得某些制造商尝试在软性隐形眼镜中加入非球面设计，以减少球差，提供更卓越的视觉性能。本研究旨在评估博士伦纯视（Balafilcon A）和酷柏佰视明（Comfilcon A）两种隐形眼镜在眼内的球差和高阶像差（HOA）的差异。
20 名受试者参与了前瞻性、随机、单侧研究。右眼散瞳后使用尼德克 OPD-Scan 测量 HOA。每只眼随机佩戴-3.00D 的纯视和佰视明隐形眼镜，在 6mm 瞳孔下原位测量 HOA。采用配对 t 检验评估与基线相比佩戴隐形眼镜时的 HOA 差异。
所有受试者均成功完成了眼像差测量。统计学分析表明球差无明显变化，但其他 HOA 项有变化。使用纯视隐形眼镜时，Zernike 系数 Z（3）（1）（从 0.01μm 增加到-0.11μm）、Z（4）（-2）（从 0.01μm 增加到 0.13μm）和 Z（5）（-1）（从-0.01μm 增加到 0.03μm）增加。使用佰视明隐形眼镜时，Zernike 系数 Z（3）（3）（从 0.00μm 增加到 0.09μm）增加。
球差无统计学显著变化。纯视隐形眼镜引起 Z（3）（1）、Z（4）（-2）和 Z（5）（-1）的统计学显著增加，佰视明隐形眼镜引起 Z（3）（3）增加。仅在纯视隐形眼镜中，Z（3）（1）和 Z（4）（-2）的变化达到临床显著水平（>0.1μm）。
