Tuan K Ashley, Benoit Douglas P, O'Connor Brett
Visioneering Technologies, Incorporated, Medical Affairs, Alpharetta, GA, USA.
MyEyeDr-Mandarin, Jacksonville, FL, USA.
Clin Ophthalmol. 2024 Jul 19;18:2113-2123. doi: 10.2147/OPTH.S468699. eCollection 2024.
Employing "relative plus" (Add) power to extend the functional vision range is a primary method to correct presbyopia with contact lenses. Simultaneous vision contact lenses are typically associated with visual disturbances at higher Add powers, often resulting in compromised vision and necessitating specialized fitting methods. Among mature individuals suffering from presbyopia, we evaluated the visual performance of a catenary curve-based extended depth of focus (EDOF) optical profile contact lens with a simplified fitting process.
Mature individuals suffering from presbyopia with Add requirements of +2.00 D or more were recruited. Monocular and binocular visual acuities were obtained across optical vergences ranging from -4.00 D to +2.00 D to generate defocus curves for best spectacle-corrected distance vision (baseline) and center-distance, catenary curve-based contact lenses (catenary). A subjective questionnaire evaluating the lenses was employed.
Twenty-four mature individuals suffering from presbyopia, average age 59.2 (range: 51-68 years) and average Add requirement of +2.24 D (range +2.00 D to +2.50 D) were enrolled. Under high-contrast conditions, the catenary lens provided functional binocular vision (0.30 logMAR or better) at all optical vergences from distance to -3.50 D (equivalent to 28 cm). Participants demonstrated a significant improvement (p < 0.05) in binocular visual acuity while wearing the catenary lens with an imposed defocus of -1.50 D to -4.00 D (equivalent to object distances from 66 cm to 25 cm). Subjective ratings with the catenary lens were equivalent to those documented at baseline.
The catenary curve-based lenses provided a full range of functional vision while maintaining clear distance vision for individuals suffering from advanced presbyopia. Comparison with previous results involving this lens indicates that these findings are also generalizable to wearers with lower Add requirements. This EDOF design provides a universal Add which is sufficient for advanced presbyopia.
ClinicalTrials.gov. Identifier: NCT05495971.
利用“相对加光”（Add）光度来扩展功能性视力范围是使用隐形眼镜矫正老花眼的主要方法。同时视隐形眼镜在较高的Add光度下通常会出现视觉干扰，常常导致视力受损，因此需要专门的验配方法。在患有老花眼的成年人中，我们评估了一种基于悬链线曲线的扩展焦深（EDOF）光学轮廓隐形眼镜的视觉性能，该隐形眼镜具有简化的验配过程。
招募Add光度需求为+2.00 D或更高的患有老花眼的成年人。在从-4.00 D到+2.00 D的光学聚散度范围内获取单眼和双眼视力，以生成最佳眼镜矫正远视力（基线）以及中心距离、基于悬链线曲线的隐形眼镜（悬链线）的散焦曲线。采用一份评估镜片的主观问卷。
招募了二十四名患有老花眼的成年人，平均年龄59.2岁（范围：51 - 68岁），平均Add光度需求为+2.24 D（范围为+2.00 D至+2.50 D）。在高对比度条件下，悬链线镜片在从远到-3.50 D（相当于28厘米）的所有光学聚散度下都能提供功能性双眼视力（0.30 logMAR或更好）。佩戴施加了-1.50 D至-4.00 D散焦（相当于物距从66厘米到25厘米）的悬链线镜片时，参与者的双眼视力有显著改善（p < 0.05）。对悬链线镜片的主观评分与基线记录的评分相当。
基于悬链线曲线的镜片为患有重度老花眼的个体提供了全范围的功能性视力，同时保持了清晰的远视力。与之前涉及该镜片的结果比较表明，这些发现也适用于Add光度需求较低的佩戴者。这种EDOF设计提供了一个通用的Add光度，足以满足重度老花眼的需求。
ClinicalTrials.gov。标识符：NCT05495971。
