School of Biomedical Sciences, University of Ulster, Cromore Road, Coleraine, BT52 1SA, UK.
Graefes Arch Clin Exp Ophthalmol. 2011 May;249(5):775-81. doi: 10.1007/s00417-010-1459-x. Epub 2010 Jul 31.
In virgin eyes, the internal aberrations compensate corneal aberrations, and it has been suggested that the compensation may be feedback-driven and developmental, with active or passive adaptive mechanisms potentially responsible for the aberration auto-compensation. The purpose of this study is to investigate the internal higher order aberrations (HOA) following laser in situ keratomileusis (LASIK).
Prospective corneal and internal HOA were measured pre-operatively and 6 months post-operatively on 50 consecutive LASIK patients with the OPD-Scan.
There were increases to corneal HOA terms Z⁰₄ (0.215 ± 0.092 μm to 0.381 ± 0.180 μm), Z⁰₆ (0.002 ± 0.018 μm to 0.049 ± 0.034 μm) and Z⁴₆ (0.010 ± 0.017 μm to 0.018 ± 0.016 μm) with corresponding increases to internal HOA terms Z⁰₄ (-0.176 ± 0.102 μm to -0.218 ± 0.121 μm), Z⁰₆ (0.004 ± 0.022 μm to -0.010 ± 0.036 μm) and Z⁴₆ (0.008 ± 0.106 μm to -0.015 ± 0.054 μm). The increases in internal aberrations attenuated the increase in corneal aberrations, providing an overall lower quantity of total aberration. A greater increase in corneal spherical aberration and associated compensation was found to occur with greater degrees of attempted myopic correction.
Corneal spherical aberration and Z⁴₆increased with corresponding increases in the internal spherical aberration and Z⁴₆ following LASIK. This may be an active compensatory mechanism of the internal optics to change, in order to reduce the effect of induced corneal HOA.
在正常的眼睛中,内部像差补偿了角膜像差,有人提出这种补偿可能是反馈驱动和发育性的,主动或被动的适应机制可能是像差自动补偿的原因。本研究的目的是探讨 LASIK 术后的内部高阶像差(HOA)。
对 50 例连续接受 LASIK 治疗的患者,使用 OPD-Scan 术前和术后 6 个月分别测量角膜和内部 HOA。
角膜 HOA 项 Z⁰₄(0.215±0.092μm 至 0.381±0.180μm)、Z⁰₆(0.002±0.018μm 至 0.049±0.034μm)和 Z⁴₆(0.010±0.017μm 至 0.018±0.016μm)均有增加,相应的内部 HOA 项 Z⁰₄(-0.176±0.102μm 至-0.218±0.121μm)、Z⁰₆(0.004±0.022μm 至-0.010±0.036μm)和 Z⁴₆(0.008±0.106μm 至-0.015±0.054μm)也有增加。内部像差的增加减弱了角膜像差的增加,提供了总体较低的总像差量。发现角膜球差和相关补偿的增加与试图矫正的近视程度的增加成正比。
LASIK 术后角膜球差和 Z⁴₆增加,相应的内部球差和 Z⁴₆也增加。这可能是内部光学改变的主动补偿机制,以减少诱导角膜 HOA 的影响。