Department of Anesthesia and Pain Medicine, School of Medicine, Pusan National University, 1-10 Ami-dong, Seo-gu, Busan 602-739, Korea.
J Anesth. 2010 Oct;24(5):783-5. doi: 10.1007/s00540-010-0995-1. Epub 2010 Aug 7.
We report the case of a 46-year-old woman presenting with postoperative bilateral cerebral visual loss that was initially misinterpreted as an irreversible ischemic event. Magnetic resonance imaging of the brain showed high signal intensity on T2-weighted and fluid-attenuated inversion recovery images and normal signal intensity on diffusion-weighted images of the posterior lobe, which mostly disappeared with the improvement of clinical symptoms. Subsequent diagnosis revealed posterior reversible encephalopathy syndrome (PRES). Recognition of PRES as the correct diagnosis led to the appropriate management strategy and the recovery of normal vision. Differentiation from acute cerebral ischemia is important in order to prevent permanent vision loss due to delay in initiating prompt and vigorous treatment of exacerbating factors, such as intermittent hypertension. We believe that it is important for anesthesiologists and critical care physicians to accurately diagnose PRES in view of the key differences in the management of similarly presenting conditions.
我们报告了一例 46 岁女性,术后出现双侧大脑视觉丧失,最初被误诊为不可逆的缺血性事件。脑部磁共振成像显示 T2 加权和液体衰减反转恢复图像上的高信号强度,而扩散加权图像上的后叶信号强度正常,随着临床症状的改善,这些信号大多消失。随后的诊断显示为后部可逆性脑病综合征(PRES)。将 PRES 识别为正确的诊断导致了适当的管理策略和视力的恢复。与急性脑缺血的鉴别很重要,以防止由于延误开始强化治疗加重因素(如间歇性高血压)而导致视力永久丧失。鉴于类似表现的情况在管理上存在关键差异,我们认为麻醉师和重症监护医生准确诊断 PRES 非常重要。