Septien L, Bourgeois M, Altaba A, Brenot M, Giroud M, Dumas R, Nivelon J L
Service de Pédiatrie, Hôpital d'Enfants, Dijon.
Arch Fr Pediatr. 1991 Apr;48(4):263-5.
Three cases of multiple sclerosis, characterized by disorders of superior functions such as memory loss, either isolated (1 case) or as part of a frontal syndrome (2 cases) are reported. The importance of these disorders, often presenting as the main symptoms, their good prognosis and their rarity in adulthood are underlined. From a pathophysiologic point of view, the authors discuss the role of the frontal, near the limbic area, localization of the plaques.
报告了3例多发性硬化症病例，其特征为存在如记忆丧失等高级功能障碍，其中1例为孤立性，2例为额叶综合征的一部分。强调了这些常常作为主要症状出现的功能障碍的重要性、其良好的预后以及在成年人中罕见的情况。从病理生理学角度来看，作者讨论了靠近边缘区的额叶部位斑块的作用。
