Braga Lucia W, Souza Ligia N, Najjar Yana J, Dellatolas Georges
SARAH Network, Brasilia, Brazil.
J Child Neurol. 2007 Sep;22(9):1084-9. doi: 10.1177/0883073807306246.
We studied the relationships between magnetic resonance imaging (MRI) findings and neuropsychological sequelae in children after severe traumatic brain injury. Twenty-three children ages 7-13 years underwent MRI assessment of brain lesion topography and volume and neuropsychological evaluations, more than 1 year after sustaining severe traumatic brain injury. Most children had lesions to the corpus callosum and frontal lobes. Total lesion volume and extent of cerebral atrophy did not impact on the neuropsychological evaluation. Additional relationships were observed: left frontal lesions with lower semantic verbal fluency, right occipital lesions with lower visual recognition task scores, dyscalculia with cerebellar lesions, and cerebellar damage with lower cognitive performances and lower visual recognition memory. This study demonstrates the significance of the cerebellum's role in neuropsychological outcomes after traumatic brain injury and the importance of the lesion depth classification in predicting functional results.
我们研究了重度创伤性脑损伤后儿童的磁共振成像（MRI）结果与神经心理学后遗症之间的关系。23名7至13岁的儿童在遭受重度创伤性脑损伤一年多后，接受了脑部病变地形和体积的MRI评估以及神经心理学评估。大多数儿童的胼胝体和额叶有病变。总病变体积和脑萎缩程度对神经心理学评估没有影响。还观察到其他关系：左侧额叶病变与较低的语义言语流畅性相关，右侧枕叶病变与较低的视觉识别任务得分相关，小脑病变与计算障碍相关，小脑损伤与较低的认知表现和较低的视觉识别记忆相关。这项研究证明了小脑在创伤性脑损伤后神经心理学结果中的作用的重要性，以及病变深度分类在预测功能结果中的重要性。
