El-Gilany Abdel-Hady, Hammad Sabry
College of Medicine, King Faisal University, Al-Hassa, Saudi Arabia.
Ann Saudi Med. 2010 Sep-Oct;30(5):376-80. doi: 10.4103/0256-4947.67075.
We examined the effect of body mass index in early pregnancy on pregnancy outcome since no study in Saudi Arabia has addressed this question.
This prospective cohort study involved women registered for antenatal care during the first month of pregnancy at primary health care centers in Al-Hassa, Saudi Arabia. Data was collected from records and by direct interview.
The study included 787 women. Compared to normal weight women (n=307), overweight (n=187) and obese (n=226) women were at increased risk for pregnancy-induced hypertension (RR=4.9 [95% CI 1.6-11.1] and 6.1 [95% CI 2.1-17.8], respectively), gestational diabetes (RR=4.4 [95% CI 1.2-16.3] and 8.6 [95% CI 2.6-28.8]), preeclamptic toxemia (RR=3.8 [95% CI 1.1-14.6] and 5.9 [95% CI 1.7-20.4]), urinary tract infections (RR=1.4 [95% CI 0.5-3.9] and 3.7 [95% CI 1.7-6.2]), and cesarean delivery (RR=2.0 [95% CI 1.3-3.0] in obese women). Neonates born to obese women had an increased risk for postdate pregnancy (RR=3.7 [95% CI 1.2-11.6]), macrosomia (RR=6.8 [95% CI 1.5-30.7]), low 1-minute Apgar score (RR=1.9 [95% CI 1.1-3.6]), and admission to neonatal care units (RR=2.1 [95% CI 1.2-2.7]). On the other hand, low birth weight was less frequent among obese women (RR=0.5 [95% CI 0.3-0.9]) while the risk was high among underweight women (RR=2.3 [95% CI 1.4-3.8]).
Even with adequate prenatal care, overweight and obesity can adversely affect pregnancy outcomes.
由于沙特阿拉伯尚无研究探讨这一问题,我们研究了孕早期体重指数对妊娠结局的影响。
这项前瞻性队列研究纳入了在沙特阿拉伯哈萨初级卫生保健中心妊娠第一个月登记进行产前检查的女性。数据通过记录和直接访谈收集。
该研究纳入了787名女性。与体重正常的女性(n = 307)相比,超重(n = 187)和肥胖(n = 226)女性发生妊娠高血压的风险增加(相对风险分别为4.9 [95%可信区间1.6 - 11.1]和6.1 [95%可信区间2.1 - 17.8])、妊娠期糖尿病(相对风险分别为4.4 [95%可信区间1.2 - 16.3]和8.6 [95%可信区间2.6 - 28.8])、先兆子痫(相对风险分别为3.8 [95%可信区间1.1 - 14.6]和5.9 [95%可信区间1.7 - 20.4])、泌尿系统感染(相对风险分别为1.4 [95%可信区间0.5 - 3.9]和3.7 [95%可信区间1.7 - 6.2]),肥胖女性剖宫产的风险也增加(相对风险为2.0 [95%可信区间1.3 - 3.0])。肥胖女性分娩的新生儿过期妊娠风险增加(相对风险为3.7 [95%可信区间1.2 - 11.6])、巨大儿风险增加(相对风险为6.8 [95%可信区间1.5 - 30.7])、1分钟阿氏评分低的风险增加(相对风险为1.9 [95%可信区间1.1 - 3.6])以及入住新生儿重症监护病房的风险增加(相对风险为2.1 [95%可信区间1.2 - 2.7])。另一方面,肥胖女性低出生体重的发生率较低(相对风险为0.5 [95%可信区间0.3 - 0.9]),而体重过轻的女性风险较高(相对风险为2.3 [95%可信区间1.4 - 3.8])。
即使有足够的产前护理,超重和肥胖仍会对妊娠结局产生不利影响。