Ohya Tatsuo, Sueyoshi Masuo
Kyushu Research Station, Environmental/Enzootic Diseases Research Team, National Institute of Animal Health, Kagoshima, Japan.
J Vet Med Sci. 2010 Dec;72(12):1651-3. doi: 10.1292/jvms.10-0271. Epub 2010 Aug 6.
The antimicrobial susceptibilities of 72 Brachyspira hyodysenteriae isolates collected from clinical cases of swine dysentery (SD) in 11 prefectures in Japan between 1985 and 2009 were investigated by an agar dilution method using five antimicrobial agents. There is a tendency of Japanese field isolates of B. hyodysenteriae to acquire resistance to the main antimicrobials used in SD treatment such as tiamulin, valnemulin, and efrotomycin. A responsible approach for selection and use of antimicrobial agents is required for SD treatment.
1985年至2009年间，从日本11个县的猪痢疾（SD）临床病例中收集了72株猪痢疾短螺旋体分离株，采用琼脂稀释法，使用5种抗菌药物对其药敏性进行了研究。日本猪痢疾短螺旋体的田间分离株有对用于SD治疗的主要抗菌药物如泰妙菌素、沃尼妙林和恩氟沙星产生耐药性的趋势。SD治疗需要对抗菌药物的选择和使用采取负责任的方法。
