Langford H G, Cushman W C, Hsu H
Department of Medicine University of Mississippi Medical Center, Jackson.
Am J Hypertens. 1991 May;4(5 Pt 1):399-403. doi: 10.1093/ajh/4.5.399.
In a 10-week trial of the effect of 80 mEq KCl/day on blood pressure, the following biochemical changes were noted: plasma renin activity (PRA), originally significantly lower in blacks than whites, increased to the same level as whites after K supplementation. A similar trend was noted with aldosterone. KCl increased creatinine excretion in blacks and whites, and lowered Ca excretion in blacks. These results suggest that the low PRA found in blacks is due, at least in part, to low K intake, and not to genetic causes.
在一项为期10周、每日服用80毫当量氯化钾对血压影响的试验中，观察到以下生化变化：血浆肾素活性（PRA）最初在黑人中显著低于白人，补钾后升至与白人相同水平。醛固酮也有类似趋势。氯化钾增加了黑人和白人的肌酐排泄，并降低了黑人的钙排泄。这些结果表明，黑人中发现的低PRA至少部分是由于钾摄入不足，而非遗传原因。
