Pathak D R, Pike M C, Key C R, Teaf S R, Bartow S A
Department of Family, Community, University of New Mexico School of Medicine, Albuquerque.
Br J Cancer. 1991 Jun;63(6):1005-9. doi: 10.1038/bjc.1991.218.
The relationship of reproductive factors, such as nulliparous vs ever-parous status, age at first birth, and total parity, with morphologic prevalence of fibrocystic changes were examined using autopsy material from three ethnic/racial groups at varying risks for breast cancer. Although there was a trend toward a protective effect of ever-parous status, there was no statistically significant difference in the prevalence of fibrocystic disease in any group defined by parity status. The ethnic differences in the prevalence of fibrocystic changes were not explained by the differences in parity status distribution for the three ethnic/racial groups.
利用来自三个患乳腺癌风险各异的种族/民族群体的尸检材料,研究了未生育与已生育状态、初产年龄和总产次等生殖因素与纤维囊性变形态学患病率之间的关系。尽管已生育状态有一定的保护作用趋势,但在根据产次状态定义的任何组中,纤维囊性疾病的患病率均无统计学显著差异。纤维囊性变患病率的种族差异无法用三个种族/民族群体产次状态分布的差异来解释。