Degreef Ilse, De Smet Luc
Department of Orthopaedic Surgery, University Hospitals of Leuven, Campus Pellenberg, Belgium.
Acta Orthop Belg. 2010 Jun;76(3):316-20.
Dupuytren's disease has been the subject of numerous epidemiological surveys attempting to expand our knowledge on its origin and spread. In Flanders, although numerous studies on surgical outcome have been reported, information on prevalence of Dupuytren's disease is lacking. Therefore, Flanders' population in a non-hospital environment was studied by a clinical evaluation performed by a single hand specialist. Five different market places spread geographically in the 5 Flemish provinces of Belgium were visited to examine the hands of randomly chosen individuals over 50 years old visiting the market. In all, 500 people were examined; Dupuytren's disease was found to be present in 32% of the population. Nodules without finger contractures (stage 1) were seen in 24% of the population, in comparable proportions in males (28%) and females (20%). However, finger contractures (stage 2) were seen in 8%, significantly more often in males (11%) than in females (4%). The prevalence of stage 1 is somewhat lower in individuals over 80 years old. In men, the incidence of stage 2 was found to increase with age. These findings were compared with literature data on the prevalence of Dupuytren's disease in other countries and populations. It appears that, similar to northern Europe, Dupuytren's disease is also a common disease in Flanders.
杜普伊特伦挛缩病一直是众多流行病学调查的主题，这些调查旨在拓展我们对其起源和传播的认识。在佛兰德地区，尽管已有大量关于手术结果的研究报告，但关于杜普伊特伦挛缩病患病率的信息却很匮乏。因此，一位手部专科医生通过临床评估对非医院环境下的佛兰德人群进行了研究。研究人员走访了比利时佛兰德省5个地理区域分布的不同市场，检查随机挑选的50岁以上前来市场的人员的手部情况。总共检查了500人；发现32%的人群患有杜普伊特伦挛缩病。24%的人群出现了无手指挛缩的结节（1期），男性（28%）和女性（20%）的比例相近。然而，8%的人群出现了手指挛缩（2期），男性（11%）明显比女性（4%）更常见。80岁以上人群中1期的患病率略低。在男性中，2期的发病率随年龄增长而增加。这些研究结果与其他国家和人群中杜普伊特伦挛缩病患病率的文献数据进行了比较。结果显示，与北欧类似，杜普伊特伦挛缩病在佛兰德地区也是一种常见疾病。
