Department of Chemistry, Faculty of Engineering, and the Center for Nanoscale Science and Engineering, University of Georgia, Athens, Georgia 30602, USA.
J Am Chem Soc. 2010 Aug 18;132(32):11024-6. doi: 10.1021/ja105066t.
Surfaces containing reactive ester polymer brushes were functionalized with cyclopropenone-masked dibenzocyclooctynes for the light activated immobilization of azides using catalyst-free click chemistry. The photodecarbonylation reaction in the amorphous brush layer is first order for the first 45 s with a rate constant of 0.022 s(-1). The catalyst-free cycloaddition of surface bound dibeznocyclooctynes proceeds rapidly in the presence of azides under ambient conditions. Photolithography using a shadow mask was used to demonstrate patterning with multiple azide containing molecules. This surface immobilization strategy provides a general and facile platform for the generation of multicomponent surfaces with spatially resolved chemical functionality.
表面含有反应性酯聚合物刷的功能化环丙烯酮掩蔽二苯并环辛炔的光激活固定叠氮化物使用无催化剂点击化学。在非晶态刷层中的光脱羰反应是第一次的前 45 秒的速率常数为 0.022 s(-1)。无催化剂环加成表面结合二苯并环辛炔迅速进行在存在下叠氮化物在环境条件下。光刻使用掩模来证明与多个含有叠氮化物的分子的图案化。这种表面固定化策略提供了一个通用的和简单的平台，用于生成具有空间分辨化学功能的多组分表面。
