Takahashi Saori, Tokiwano Tetsuo, Hata Keishi, Kodama Ikuko, Hokari Mika, Suzuki Nao, Yoshizawa Yuko, Gotoh Takeshi
Akita Research Institute of Food and Brewing, Sanuki, Arayamachi, Akita, Japan.
Biosci Biotechnol Biochem. 2010;74(8):1713-5. doi: 10.1271/bbb.100233. Epub 2010 Aug 7.
We found renin inhibitory activity in rice. The physico-chemical data on the isolated inhibitors were identical to those of oleic acid and linoleic acid. Oleic acid and linoleic acid competitively inhibited renin activity, with K(i) values of 15.8 and 19.8 microM respectively. Other unsaturated free fatty acids also inhibited renin activity, but saturated fatty acids had no effect on it.