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[公猪尿液中睾酮和雄烯二酮的排泄与睾丸内分泌功能的关系]

[Elimination of testosterone and androstendione in the urine of boars in relation to the incretory function of the testes].

作者信息

Navrátil S, Matousková O

出版信息

Vet Med (Praha). 1978 Feb;23(2):77-86.

PMID:207004
Abstract

The elimination of testosterone and androstendion in the urine was tested in six sexually mature boars. The administration of chorionic gonadotropin to intact animals resulted in a marked, statistically significant, rise of the amounts of excreted testosterone and, in part of the cases, androstendion. The responses were individual. Bilateral orchidectomy caused a statistically highly significant decrease of the elimination of both steroids under study without pronounced adrenocortical compensation. The administration of the adrenocorticotropic hormone to castrated boars did not exert any significant influence on the excretion of the substances studied. The use of chorionic gonadotropin given to the castrated boars did not produce any significant changes in the elimination of hormones. It has been inferred that testosterone as well as androstendion in the urine of boars are almost exclusively of testicular origin and that the response of the values of both steroids to the administration of chorionic gonadotropin is specific after testicular incretion. The discussion concerns the importance of these findings for the evaluation of the incretion reserve of the testes and for the diagnosis of incretion hypogonadism in boars.

摘要

对六头性成熟公猪尿液中睾酮和雄烯二酮的排泄情况进行了检测。对未阉割的动物注射绒毛膜促性腺激素后,排泄的睾酮量显著增加,且具有统计学意义,部分情况下雄烯二酮的排泄量也有所增加。这些反应存在个体差异。双侧睾丸切除导致所研究的两种类固醇的排泄量在统计学上极显著降低,且无明显的肾上腺皮质代偿。对公猪去势后注射促肾上腺皮质激素,对所研究物质的排泄没有产生任何显著影响。对公猪去势后使用绒毛膜促性腺激素,激素排泄量未发生任何显著变化。据推断,公猪尿液中的睾酮和雄烯二酮几乎完全来源于睾丸,且睾丸分泌后,两种类固醇的值对绒毛膜促性腺激素给药的反应具有特异性。讨论内容涉及这些发现对于评估公猪睾丸分泌储备以及诊断公猪分泌性腺功能减退的重要性。

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