Katsiia G V, Gorlushkin V M, Todua T N, Goncharov N P
Probl Endokrinol (Mosk). 1984 Sep-Oct;30(5):68-71.
Radioimmunoassay was used to study secretion of Papio hamadryas testis under stimulation with human chorionic gonadotropin (hCG). It was discovered that hCG had an acute stimulating effect on testicular secretion of testosterone, androstendione and 17-hydroxyprogesterone. It was demonstrated that repeated stimulation with hCG in the presence of the maximal secretory response of the testis (24 h after the first injection and in the presence of its partial reduction (after 72 h) did not provoke any additional rise of testosterone secretion. Unlike the initial response, repeated stimulation with hCG gave rise to dissociation in the time-course of testosterone and 17-hydroxyprogesterone responses. The data obtained attest to temporary "desensitization" of the testis to repeated stimulation with hCG.
采用放射免疫分析法研究了绒毛膜促性腺激素（hCG）刺激下阿拉伯狒狒睾丸的分泌情况。结果发现，hCG对睾丸分泌睾酮、雄烯二酮和17-羟孕酮具有急性刺激作用。结果表明，在睾丸最大分泌反应（首次注射后24小时）存在的情况下，以及在其部分降低（72小时后）的情况下，用hCG重复刺激不会引起睾酮分泌的任何额外增加。与初始反应不同，用hCG重复刺激会导致睾酮和17-羟孕酮反应的时间进程出现解离。所获得的数据证明睾丸对hCG重复刺激存在暂时的“脱敏”现象。
