环状烯基硼酸半酸的合成及应用。
Cyclic alkenyl boronic half acid synthesis and applications.
机构信息
Butler University, 4600 Sunset Avenue, Indianapolis, Indiana 46208, USA.
出版信息
J Org Chem. 2010 Sep 3;75(17):6001-4. doi: 10.1021/jo1003423.
PMID:20701318
Abstract
The synthesis of cyclic alkenyl boronic half acids from vinyl and propenyl boronic esters and homoallylic alcohols by ring-closing metathesis is reported. The method is compatible with both conventional and microwave heating and comparable yields are obtained under both conditions. The cyclic alkenyl boronic acids participate in Suzuki-Miyaura coupling reactions in good yields.
摘要
本文报道了通过闭环复分解反应，由乙烯基和丙烯基硼酸酯与偕丙醇合成环状烯基硼酸半酸的方法。该方法兼容传统加热和微波加热，在这两种条件下都能获得相当的产率。环状烯基硼酸能以较好的收率参与铃木-宫浦偶联反应。
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