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布鲁氏菌病:过去、现在与未来

Brucellosis: past, present and future.

作者信息

Nicoletti P

机构信息

College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.

出版信息

Prilozi. 2010;31(1):21-32.

Abstract

AIM

To present an overview and the specificities of the biology and epidemiology, pathogenesis and diagnostics, public health aspects, vaccination and control of brucellosis as a global zoonosis.

METHODS

Of the various methods to control brucellosis in animals such as vaccination, hygiene, and test and slaughter of infected animals, widespread vaccination is the most rapid, efficient and effective procedure.

RESULTS

Despite much progress in the control and sometimes eradication of brucellosis in cattle in many countries, the situation with the disease in small ruminants is proving to be much more difficult. Political and socioeconomic problems are deterrents to success. It is a veterinary responsibility to accept the challenge to control animal brucellosis, which will then control the disease in humans. The success of the control effects will be primarily measured by a decrease in human cases.

CONCLUSION

Effective control of brucellosis requires a long-term commitment from many governmental agencies. Assistance from international animal and human health organizations in resources and expertise is necessary in many developing countries. There are no easy solutions. Research on alternative strategies in vaccines and their usage, diagnostic tests, and treatments should be encouraged.

摘要

目的

概述布鲁氏菌病作为一种全球人畜共患病在生物学、流行病学、发病机制、诊断、公共卫生方面、疫苗接种及防控的特点。

方法

在动物布鲁氏菌病的各种防控方法中,如疫苗接种、卫生措施以及对感染动物进行检测和扑杀,广泛接种疫苗是最迅速、高效且有效的程序。

结果

尽管许多国家在控制甚至有时根除牛布鲁氏菌病方面取得了很大进展,但事实证明,小反刍动物的疫病情况要困难得多。政治和社会经济问题阻碍了防控成功。控制动物布鲁氏菌病是兽医的责任,进而控制人类的该疾病。防控效果的成功将主要通过人类病例的减少来衡量。

结论

有效控制布鲁氏菌病需要许多政府机构的长期投入。在许多发展中国家,国际动物和人类健康组织在资源和专业知识方面提供援助是必要的。没有简单的解决办法。应鼓励对疫苗及其使用的替代策略、诊断测试和治疗方法进行研究。

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