Otto S D, Ritz J P, Gröne J, Buhr H J, Kroesen A J
Department of Surgery, Charité-University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203, Berlin, Germany.
World J Surg. 2010 Nov;34(11):2710-6. doi: 10.1007/s00268-010-0735-6.
The pathophysiology of rectal prolapse and intussusception has not yet been clarified. This is reflected in the multiplicity of surgical procedures. The aim of this prospective study was to measure morphological and functional changes of the pelvic floor and the rectum before and after resection rectopexy.
A total of 21 patients (mean age 60 years; 2 men, 19 women) with manifest rectal prolapse and rectoanal intussusception underwent sigmoidectomy and rectopexy with an absorbable polyglactin mesh graft. The following analyses were performed preoperatively and, on average, 15 months (range 6-21 month) postoperatively: radiologic defecography, rectal volumetry, sphincter manometry, and evaluation of clinical symptoms.
Postoperatively there was no patient with rectal prolapse, and only one with an intussusception. Rectal compliance increased from 6.4 to 10.2 ml/mmHg. Rectal volumetry showed a decrease of the thresholds for the sensation of "desire to defecate" and "maximal tolerated volume" (100-75 ml, 175-150 ml). Postoperatively, there was a higher level of the pelvic floor during contraction. The anorectal angle, vector volume, radial asymmetry, sphincter length, and resting and squeezing pressures were unchanged. Surgery improved rectal evacuation (p = 0.03), continence (p = 0.01), stool consistency (p = 0.03), and warning period (p = 0.01). Patients' personal assessment showed an improved overall satisfaction.
Resection rectopexy is a reliable method for treating rectal prolapse and rectoanal intussusception with clear improvement of the patient's clinical symptoms. The restored anorectal function can be attributed to improved rectal compliance, a lower sensory threshold, an elevation of the pelvic floor during squeezing, and an improved rectal evacuation.
直肠脱垂和套叠的病理生理学尚未阐明。这反映在手术方法的多样性上。这项前瞻性研究的目的是测量直肠固定切除术前和术后盆底及直肠的形态和功能变化。
共有21例(平均年龄60岁;男性2例,女性19例)明显直肠脱垂和直肠肛管套叠患者接受了乙状结肠切除术及使用可吸收聚乙醇酸网片移植的直肠固定术。术前及术后平均15个月(范围6 - 21个月)进行了以下分析:放射学排粪造影、直肠容量测定、括约肌测压及临床症状评估。
术后无直肠脱垂患者,仅有1例发生套叠。直肠顺应性从6.4增加至10.2 ml/mmHg。直肠容量测定显示“便意”和“最大耐受容量”的阈值降低(分别从100 - 75 ml、175 - 150 ml降低)。术后收缩时盆底水平升高。肛管直肠角、矢量容积、径向不对称性、括约肌长度以及静息和收缩压力均未改变。手术改善了直肠排空(p = 0.03)、控便能力(p = 0.01)、大便性状(p = 0.03)及预警期(p = 0.01)。患者个人评估显示总体满意度提高。
直肠固定切除术是治疗直肠脱垂和直肠肛管套叠的可靠方法,可明显改善患者临床症状。恢复的肛管直肠功能可归因于直肠顺应性改善、感觉阈值降低、收缩时盆底抬高以及直肠排空改善。