Department of Electronics and Computer Technology, Gazi University, Teknikokullar, Ankara, Turkey.
J Med Syst. 2010 Dec;34(6):1059-71. doi: 10.1007/s10916-009-9324-3. Epub 2009 Jun 9.
Brain temperature fluctuations occur in consequence of physiological and pathophysiological conditions and indicate changes in brain metabolism, cerebral blood flow (CBF), brain functions and neural damage. Lowering the brain temperature of patients with traumatic brain injuries achieves considerable improvements. When the human brain is cooled down to 30°C, it switches to a sub functional regime where it can live longer with less oxygen, glucose and other supplies. Fluctuations in brain temperature cause changes in brain parameters which can be measured by electroencephalogram (EEG) and transcranial Doppler (TCD). It is very important to understand the temperature dependencies of brain's electrical activity and blood flow and their interrelations considering the good clinical results achieved by lowering the brain temperature of neurologically injured patients. Since protecting the patient's brain is of primary importance in many fields including cardiology, neurology, traumatology and anesthesia it can be clearly seen that this subject is very important. In this study, we survey the "state-of-the-art" in analysis of EEG and TCD brain parameters changing with temperature and present further research opportunities.
脑温度波动是由生理和病理生理条件引起的，表明脑代谢、脑血流（CBF）、脑功能和神经损伤的变化。降低创伤性脑损伤患者的脑温可取得显著改善。当人类大脑冷却到 30°C 时，它会切换到亚功能状态，在这种状态下，它可以在更少的氧气、葡萄糖和其他供应的情况下存活更长时间。脑温度波动引起脑参数的变化，可以通过脑电图（EEG）和经颅多普勒（TCD）来测量。考虑到降低神经损伤患者脑温所取得的良好临床效果，了解脑电活动和血流的温度依赖性及其相互关系非常重要。由于在心脏病学、神经病学、创伤学和麻醉学等许多领域保护患者的大脑至关重要，可以清楚地看到这个主题非常重要。在这项研究中，我们调查了 EEG 和 TCD 脑参数随温度变化的“最新进展”，并提出了进一步的研究机会。
