Department of Electrical and Computer Engineering, Isfahan University of Technology, Isfahan, Iran.
J Med Syst. 2010 Dec;34(6):1043-58. doi: 10.1007/s10916-009-9323-4. Epub 2009 Jul 14.
We present an automated method for segmentation of epithelial cells in images taken from ThinPrep scenes by a digital camera in a cytology lab. The method covers both steps of localization of cell objects in low resolution and detection of cytoplasm and nucleus boundary in high resolution. The underlying method makes use of geometric active contours as a powerful tool of segmentation. We also provide the analysis of the connected cells. For this purpose an automatic circular decomposition method is incorporated and adapted to the application by changing its segmentation condition. The results are evaluated numerically and compared with those of previous work in literature.
我们提出了一种自动化方法,用于对细胞学实验室中的数字相机拍摄的 ThinPrep 场景中的上皮细胞进行分割。该方法涵盖了在低分辨率下定位细胞对象和在高分辨率下检测细胞质和细胞核边界的两个步骤。基础方法利用几何活动轮廓作为分割的强大工具。我们还提供了对连接细胞的分析。为此,我们采用了自动圆形分解方法,并通过改变其分割条件将其应用于该方法。结果进行了数值评估,并与文献中的先前工作进行了比较。