光致旋光催化剂用于仲醇的动态动力学拆分。

Photoactivated racemization catalyst for dynamic kinetic resolution of secondary alcohols.

机构信息

Department of Chemistry Pohang University of Science and Technology (POSTECH), San 31 Hyojadong, Pohang, Kyeongbuk 790-784, Republic of Korea.

出版信息

J Org Chem. 2010 Aug 20;75(16):5740-2. doi: 10.1021/jo1009036.

DOI:10.1021/jo1009036

PMID:20704447

Abstract

Household fluorescent light activates a diruthenium complex to generate catalytic species highly active for the racemization of secondary alcohols under ambient conditions. This catalyst system is applicable for the chemoenzymatic dynamic kinetic resolution of racemic alcohols to give optically pure acetates under mild conditions.

摘要

家用荧光灯激活双钌配合物，在环境条件下生成用于仲醇外消旋体的高活性催化物种。该催化剂体系适用于在温和条件下通过化学酶动力学拆分对映醇，以得到光学纯的醋酸酯。