Department of Cardiology, The Heart Center, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
JACC Cardiovasc Imaging. 2010 Aug;3(8):854-9. doi: 10.1016/j.jcmg.2010.06.007.
Functional assessment of continuous-flow left ventricular assist devices (LVADs) is usually performed with the patient at rest. This study compared echocardiographic indices of contraction and filling pressure with invasive measures in 12 ambulatory LVAD patients undergoing symptom-limited bicycle exercise. Exercise induced an increase in cardiac output, systolic pulmonary artery pressure, and diastolic pulmonary artery pressure. Although no changes in left ventricular dimensions or fractional shortening were seen on echocardiography, systolic mitral annular motion (S') increased significantly (in parallel with cardiac output) and diastolic E/e' ratio decreased (correlating inversely with diastolic pulmonary artery pressure). These findings emphasize the potential role of exercise echocardiography in studying exercise hemodynamics in LVAD patients.
对左心室辅助装置（LVAD）的功能评估通常在患者休息时进行。本研究比较了 12 名进行症状限制自行车运动的流动 LVAD 患者的收缩和充盈压的超声心动图指数与有创指标。运动引起心输出量、收缩肺动脉压和舒张肺动脉压增加。尽管超声心动图未见左心室尺寸或节段缩短的变化，但二尖瓣环收缩期运动（S'）显著增加（与心输出量平行），舒张期 E/e'比值降低（与舒张期肺动脉压呈反比）。这些发现强调了运动超声心动图在研究 LVAD 患者运动血液动力学中的潜在作用。
