Mwangemi P M
Roswell Park Mamorial Institute, Buffalo, N.Y.
East Afr Med J. 1991 Mar;68(3):190-6.
Primary cerebral non-Hodgkin's lymphoma of the brain are very rare neoplasms. The pertinent data describing these tumours have been gathered in retrospect and from reviews of postmortem materials. There has been increased interest in this disorder in recent years because of improved diagnostic capabilities. The computerized axial tomography and radiopharmaceutical uptake brain scintiscans are invaluable prebiopsy non-invasive investigative procedures. Brain biopsy and minimal tumour resection are nowadays the preferred modes of surgical treatment. Because more radical surgery and whole brain radiation have failed to control the high rate of systemic relapses, it is generally recommended that Chemotherapy should be incorporated into the primary treatment plan. High dose intravenous methotrexate has been shown to be effective in treatment of residual lymphoma and systemic recurrent tumours.
原发性脑非霍奇金淋巴瘤是非常罕见的肿瘤。描述这些肿瘤的相关数据是通过回顾和对尸检材料的综述收集而来的。近年来，由于诊断能力的提高，人们对这种疾病的兴趣有所增加。计算机断层扫描和放射性药物摄取脑闪烁扫描是活检前非常有价值的非侵入性检查程序。脑活检和肿瘤最小化切除是目前首选的手术治疗方式。由于更激进的手术和全脑放疗未能控制高比例的全身复发，一般建议在初始治疗方案中加入化疗。高剂量静脉注射甲氨蝶呤已被证明对治疗残留淋巴瘤和全身复发性肿瘤有效。
