Department of Surgery, Trinity Centre for Health Sciences, Trinity College Dublin, St James' Hospital, Dublin 8, Ireland.
Surgeon. 2010 Oct;8(5):270-9. doi: 10.1016/j.surge.2010.06.004.
The short bowel syndrome (SBS) is a state of malabsorption following intestinal resection where there is less than 200 cm of intestinal length. The management of short bowel syndrome can be challenging and is best managed by a specialised multidisciplinary team. A good understanding of the pathophysiological consequences of resection of different portions of the small intestine is necessary to anticipate and prevent, where possible, consequences of SBS. Nutrient absorption and fluid and electrolyte management in the initial stages are critical to stabilisation of the patient and to facilitate the process of adaptation. Pharmacological adjuncts to promote adaptation are in the early stages of development. Primary restoration of bowel continuity, if possible, is the principle mode of surgical treatment. Surgical procedures to increase the surface area of the small intestine or improve its function may be of benefit in experienced hands, particularly in the paediatric population. Intestinal transplant is indicated at present for patients who have failed to tolerate long-term parenteral nutrition but with increasing experience, there may be a potentially expanded role for its use in the future.
短肠综合征（SBS）是一种在肠道切除后发生的吸收不良状态，其肠道长度不足 200 厘米。SBS 的治疗具有挑战性，最好由专门的多学科团队进行管理。需要充分了解小肠不同部位切除的病理生理后果，以便尽可能预测和预防 SBS 的后果。在初始阶段，营养吸收以及液体和电解质的管理对于稳定患者并促进适应过程至关重要。促进适应的药物辅助治疗仍处于早期发展阶段。如果可能，恢复肠道连续性是手术治疗的主要模式。在有经验的医生手中，增加小肠表面积或改善其功能的手术程序可能会有帮助，尤其是在儿科人群中。目前，对于无法耐受长期肠外营养的患者，肠移植是一种治疗方法，但随着经验的增加，未来其应用可能会有更大的潜力。
