Department of Ophthalmology, West Virginia University, Morgantown, West Virginia, USA.
Ophthalmology. 2011 Jan;118(1):47-51. doi: 10.1016/j.ophtha.2010.04.027. Epub 2010 Aug 14.
To evaluate the short-term repeatability of diurnal intraocular pressure (IOP) patterns in eyes with primary open-angle glaucoma (POAG).
Observational cohort study.
Forty-seven subjects with treated POAG.
Subjects underwent assessment of IOP using Goldmann tonometry every 2 hours from 0800 to 2000 on 2 visits 1 week apart. Intervisit agreement of IOP by time point and of IOP change between time points was assessed using intraclass correlation coefficients (ICCs).
Diurnal IOP patterns.
Between-visit agreement of IOP values at each time point was generally fair to good, with ICCs ranging from 0.45 to 0.71 in right eyes and from 0.51 to 0.71 in left eyes. Between-visit agreement of IOP change over time periods between time points was uniformly poor, with ICCs ranging from -0.08 to 0.38 in right eyes and from -0.11 to 0.36 in left eyes.
Treated POAG patients do not manifest a repeatable diurnal IOP pattern from day to day when measured by Goldmann tonometry. Measurement of single-day IOP variation poorly characterized short-term IOP variation.
评估原发性开角型青光眼（POAG）患者日间眼压（IOP）模式的短期重复性。
观察性队列研究。
47 名经治疗的 POAG 患者。
患者在两次就诊期间，每 2 小时使用 Goldmann 眼压计测量IOP，时间范围为 0800 至 2000，两次就诊间隔 1 周。通过组内相关系数（ICCs）评估各时间点 IOP 的访间一致性和时间点之间 IOP 变化的一致性。
日间 IOP 模式。
每次就诊时，各时间点的IOP 值的访间一致性通常为中等至良好，右眼的 ICC 范围为 0.45 至 0.71，左眼的 ICC 范围为 0.51 至 0.71。时间点之间时间段内的 IOP 变化的访间一致性均较差，右眼的 ICC 范围为-0.08 至 0.38，左眼的 ICC 范围为-0.11 至 0.36。
用 Goldmann 眼压计测量时，经治疗的 POAG 患者每天的日间 IOP 模式并不具有可重复性。单次测量的 IOP 波动并不能很好地描述短期 IOP 波动。
