Lawson L, Habib A G, Okobi M I, Idiong D, Olajide I, Emenyonu N, Onuoha N, Cuevas L E, Ogiri S O
Zankli Medical Centre, Abuja, Nigeria.
Ann Afr Med. 2010 Jul-Sep;9(3):184-7. doi: 10.4103/1596-3519.68355.
Drug resistant tuberculosis (TB) has lately emerged and it represents a serious public health problem. We set out to determine drug resistance among TB patients.
Using automated BACTEC cultures, multidrug resistant-tuberculosis (MDR-TB) was investigated in 117 diagnosed cases in Abuja, Nigeria.
Ten (31%) of 32 culture-positive patients were resistant to at least one and four (13%) to all of the four drugs tested. No association between drug resistance and human immunodeficiency virus (HIV) infection was found.
MDR-TB is present in Nigeria and larger studies are urgently required. TB clinical management and control efforts should be improved.
耐药结核病最近出现，它是一个严重的公共卫生问题。我们着手确定结核病患者中的耐药情况。
使用自动化BACTEC培养法，对尼日利亚阿布贾117例确诊病例进行耐多药结核病（MDR-TB）调查。
32例培养阳性患者中有10例（31%）对至少一种药物耐药，4例（13%）对所有四种测试药物均耐药。未发现耐药与人类免疫缺陷病毒（HIV）感染之间存在关联。
尼日利亚存在耐多药结核病，迫切需要开展更大规模的研究。应改进结核病的临床管理和防控工作。
