Kim Chi Yeon, Lee Seung Hun, Oh Chee Won
Department of Dermatology, School of Medicine, Gyeongsang National University & Gyeongsang Institute of Health Science, Jinju, Korea.
Ann Dermatol. 2010 Aug;22(3):370-2. doi: 10.5021/ad.2010.22.3.370. Epub 2010 Aug 5.
As the survival from cutaneous malignant melanoma and its clinical concerns have been steadily increasing, the possibility has been raised of an increased risk of second primary cancers in the patients with malignant melanoma. Especially, recent studies have identified an association between cutaneous malignant melanoma and thyroid carcinoma. We here report on a case of cutaneous malignant melanoma that developed in a 61-year-old female patient who had hypothyroidism caused by papillary thyroid carcinoma. We suggest that the individuals who have cutaneous malignant melanoma may be predisposed to other primary cancers and especially thyroid carcinoma. Continuous monitoring of the thyroid function in melanoma patients is required because hypothyroidism can worsen due to malignant melanoma and this is probably associated with thyroid carcinoma.
随着皮肤恶性黑色素瘤患者生存率的稳步提高及其临床关注度的不断增加，恶性黑色素瘤患者发生第二原发性癌症的风险增加的可能性也随之出现。特别是，最近的研究已经确定皮肤恶性黑色素瘤与甲状腺癌之间存在关联。我们在此报告一例皮肤恶性黑色素瘤病例，该病例发生在一名61岁的女性患者身上，她患有由乳头状甲状腺癌引起的甲状腺功能减退症。我们认为，患有皮肤恶性黑色素瘤的个体可能易患其他原发性癌症，尤其是甲状腺癌。黑色素瘤患者需要持续监测甲状腺功能，因为甲状腺功能减退症可能会因恶性黑色素瘤而恶化，这可能与甲状腺癌有关。
