Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada.
Int J Clin Oncol. 2011 Feb;16(1):67-70. doi: 10.1007/s10147-010-0113-2. Epub 2010 Aug 17.
We report an unusual case of a primary osteosarcoma of the lung in an asymptomatic 77-year-old male, who underwent lobectomy with complete resection of the lung lesion. His pattern of relapse was to multiple lymph nodes. The first relapse was 11 weeks after lobectomy in subcarinal lymph nodes, confirmed on needle aspiration to be consistent with sarcoma. Given his excellent performance status, this was treated with radical radiotherapy to 70 Gy in 35 fractions with good control. He relapsed to other lymph node regions. A biopsy of the external iliac lymph node was done and revealed osteoid production, consistent with osteosarcoma. He received palliative radiotherapy to several nodal areas with good clinical response. We review the literature of this rare tumor with an unusual pattern of relapse.
我们报告了一例不常见的无症状 77 岁男性肺原发性骨肉瘤病例，该患者接受了肺病变的肺叶切除术和完全切除术。他的复发模式是多个淋巴结。第一次复发是在肺叶切除术后 11 周，在隆突下淋巴结中发现，经针吸活检证实为肉瘤。鉴于他的良好表现状态，采用根治性放疗，70Gy 分 35 次进行，控制良好。他又复发到其他淋巴结区域。对髂外淋巴结进行了活检，发现有骨样组织生成，符合骨肉瘤。他接受了姑息性放疗，对几个淋巴结区域进行了治疗，临床反应良好。我们回顾了这种罕见肿瘤具有不常见复发模式的文献。
